18 November 2005

On The Subject of Blood

I didn’t know Zimbabwe used to be called Rhodesia. I wonder if Rhodesian Ridgebacks roam the rural roads.

On the subject of blood. It’s very dirty. I think I’ve addressed this before. If you have fantasies and ideas of vampires, the whole undead thing, I think you’d do better off sucking on a potato. It’s safer, cleaner and it’s sort of undead – it thrives in darkness. While I say this, I personally have yet to come to appreciate the potato as a complex and beautiful thing. Blood may be dirty, but it’s also beautiful, historic and complicated. I wish a clever scientist with aural appreciations could find a way to convert cytokines to tones and unleash the symphony of blood. And you know it’s not just blood – it’s the entire system that’s so wonderful. It is not ‘irreducibly complex.’ The brilliance, wonder and genius of it is that it is reducible. The redundancy in the system is exactly what allows it to be a dynamic, evolving and learning system. It is mathematical, musical and mysterious.

We can break the immune system down in many ways. It’s no different than anything in this regard. For example, we can walk into a room and talk about the number of people who wear glasses versus those not wearing glasses. Similarly we can talk about the cellular versus humoral arms of the immune system. We can talk about people who write left versus right handed. We can talk about innate or acquired immunity. And in all instances there is a spectrum, a spectrum of sight, those who wear contacts, and those who perform some functions with their left hand and others with their right and of course those who fall smack dab in the middle as wholly ambidextrous.

So what’s the difference between innate and acquired immunity? Innate immunity is what we’re born with, ancient immunologic knowledge passed down generation after generation. It’s very old wisdom – very valuable. It’s our first line of defense and it’s typically extremely effective. That we carry this ancient wisdom in our blood, this intelligence, isn’t it some kind of evidence of reincarnation or at least proof that it’s really quite possible that we have other kinds of ancient wisdom that we’ve yet to really tap into and understand? When birds migrate or animals engage in certain unlearned behaviors that promote their survival, we’ll call it instinct. But what is instinct other than mysterious wisdom? And why is this wisdom mostly recognized as behavior? Haven’t you ever had the experience of knowing things and not really understanding how you know it? When people say, trust your gut, what they often mean is trust the innate wisdom that is within you – the ancient knowledge that we need to learn to get in touch with and learn how to listen to. But then I wonder, in the same way some people’s innate immunity fails to control disease, perhaps not all innate wisdom is good. Makes you think.

And acquired immunity is learned. While certain cells and functions within us are a result of ancient wisdom, to complete the system there is also the ability to learn and learn we do. We can teach cells to do new things – which is the foundation behind vaccination – to teach the immune system to recognize and respond to say a flu virus before it ever actually encounters the flu virus. Thus if and when someone becomes infected with the flu virus, the immune system is primed and ready to act – to contain and control the infection before it causes disease. A very misunderstood thing about vaccines is that they do not prevent infection, they prevent disease. But I think a very cool thing about the acquired immune system is that we are not all equal – we’re not all able to mount an effective and robust immune response to an “immunologic lesson” – we do not all learn the same. Some have immunologic learning disabilities and/or defects and often these are in discrete areas – in some instances causing no noticeable harm or effect, in other instances leaving one vulnerable to certain diseases and in other instances these defects have benefits (perhaps unintended.) And I think when we dig deeper, what we find is that on some fundamental level, something is controlling our capacity and breadth of learning. I’m apt to believe that what’s controlling our capacity and breath of immunologic learning is actually much to do with ancient wisdom, genetic information passed on through history, from the earliest days of evolution, from our mothers, mothers, mothers, mothers, mothers, mothers… and so on. So there’s that spectrum, that continuum of experience – the inability to slice diversity neatly along a line.

It seems (almost) the human condition to deny this link with the past. It seems (almost) the human condition to deny this link with the future. It’s perhaps something we need to rail against, the inability to live in the long now. Somewhere the silver cell divides.

I digress.. more on blood later. Or, well, maybe not (does it bore you?) But you know, think about it… if I touch you is there perhaps some wisdom my skin cells whisper in the ears of yours? I like to think on it – the logic of your touch, intelligent kisses, our ancients communing while we pretend we’re just having tea…

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